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An Overview of Heritable Thoracic Aortic Disease

The goals of this overview on heritable thoracic aortic aneurysms and dissections (shortened in this GeneReview to heritable thoracic aortic disease [HTAD]) are the following.

Goal 1. Define the clinical characteristics of thoracic aortic disease.

Goal 2. Review the causes of HTAD.

Goal 3. Provide a strategy for evaluation and genetic risk assessment for HTAD in a proband.

Goal 4. Inform genetic counseling and risk assessment in family members of a proband with HTAD.

Goal 5. Review management recommendations for individuals with HTAD.

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